Daniel S. Major House
Listed in Historical landmark, Ohio River Scenic Byway
22-18 Wolf Run Rd, Lawrenceburg, Indiana 47025
Built between 1857 and 1860, the Daniel S. Major House is a National Register-listed Italianate residence in Lawrenceburg, Indiana, noted for its brick construction, polygonal bay windows, low hipped roof, and two-story service wing.
Beck’s Mill
Listed in Historical landmark, Pioneer History
4433 S Becks Mill Rd, Salem, IN 47167, Salem, Indiana 47167
Historic Beck’s Mill near Salem preserves Indiana’s traditional grindstone milling heritage and is listed on the National Register of Historic Places.
Madison Historic District Historical Marker
300 E Vaughn Dr, Madison, Indiana 47250
Learn about Madison’s National Register-listed Historic District, spanning more than 130 blocks and hundreds of buildings dating from about 1812 to 1920.
Cairo Historic District
Listed in Civil War, Civil War Trails, Historical place, National Underground Railroad Network to Freedom, Ohio River Scenic Byway, Trail of Tears, Visited by Old Folks Adventures
364-398 20th St, Cairo, Illinois 62914
Explore the historic streetscape of Cairo, Illinois, a strategic river town shaped by commerce, transportation, Civil War history, and its setting near the Ohio and Mississippi Rivers.
Ashworth Archaeological Site
12815 IN-69, Mt Vernon, Indiana 47620
A nationally recognized archaeological site near Mt. Vernon, Indiana, close to the Ohio-Wabash confluence and a broader landscape of important Indigenous sites.
US Marine Hospital
Listed in Historical place, Tourist attraction
Northwestern Pkwy, Louisville, KY 40212, Louisville, Kentucky 40212
A rare surviving federal marine hospital tied to Louisville’s Ohio River history and the city’s 19th-century river trade.
Miller Grove Town National Historic Site
Listed in African American history, Historical landmark, National Underground Railroad Network to Freedom
336 Cedar Grv Rd, Simpson, Illinois 62985
Miller Grove School is a historic one-room schoolhouse near Simpson, Illinois, associated with the area’s early African American community. Listed on the National Register of Historic Places, it preserves a quiet story of education, family, and perseverance in rural southern Illinois.
Triple Whipple Iron Bridge
Old State Rd 56, Aurora, Indiana 47001
Built in 1878, Aurora's Triple Whipple Iron Bridge is a rare and striking example of 19th-century wrought-iron bridge engineering over Laughery Creek.
New York Central RR Depot – Olmsted Illinois
Listed in Historical landmark, Ohio River Scenic Byway, Railroad Depot, Visited by Old Folks Adventures
110 Depot St, Olmsted, IL 62970, Olmsted, Illinois 62970
Built in 1872, the New York Central Railroad Depot preserves Olmsted's railroad heritage. Now a museum and National Register landmark, it tells the story of the Cairo and Vincennes Railroad and the trains that helped shape southern Illinois.
Daniel S. Major House
Listed in Historical landmark, Ohio River Scenic Byway
22-18 Wolf Run Rd, Lawrenceburg, Indiana 47025
Built between 1857 and 1860, the Daniel S. Major House is a National Register-listed Italianate residence in Lawrenceburg, Indiana, noted for its brick construction, polygonal bay windows, low hipped roof, and two-story service wing.
Beck’s Mill
Listed in Historical landmark, Pioneer History
4433 S Becks Mill Rd, Salem, IN 47167, Salem, Indiana 47167
Historic Beck’s Mill near Salem preserves Indiana’s traditional grindstone milling heritage and is listed on the National Register of Historic Places.
Madison Historic District Historical Marker
300 E Vaughn Dr, Madison, Indiana 47250
Learn about Madison’s National Register-listed Historic District, spanning more than 130 blocks and hundreds of buildings dating from about 1812 to 1920.
Cairo Historic District
Listed in Civil War, Civil War Trails, Historical place, National Underground Railroad Network to Freedom, Ohio River Scenic Byway, Trail of Tears, Visited by Old Folks Adventures
364-398 20th St, Cairo, Illinois 62914
Explore the historic streetscape of Cairo, Illinois, a strategic river town shaped by commerce, transportation, Civil War history, and its setting near the Ohio and Mississippi Rivers.
Ashworth Archaeological Site
12815 IN-69, Mt Vernon, Indiana 47620
A nationally recognized archaeological site near Mt. Vernon, Indiana, close to the Ohio-Wabash confluence and a broader landscape of important Indigenous sites.
US Marine Hospital
Listed in Historical place, Tourist attraction
Northwestern Pkwy, Louisville, KY 40212, Louisville, Kentucky 40212
A rare surviving federal marine hospital tied to Louisville’s Ohio River history and the city’s 19th-century river trade.
Miller Grove Town National Historic Site
Listed in African American history, Historical landmark, National Underground Railroad Network to Freedom
336 Cedar Grv Rd, Simpson, Illinois 62985
Miller Grove School is a historic one-room schoolhouse near Simpson, Illinois, associated with the area’s early African American community. Listed on the National Register of Historic Places, it preserves a quiet story of education, family, and perseverance in rural southern Illinois.
Triple Whipple Iron Bridge
Old State Rd 56, Aurora, Indiana 47001
Built in 1878, Aurora's Triple Whipple Iron Bridge is a rare and striking example of 19th-century wrought-iron bridge engineering over Laughery Creek.
New York Central RR Depot – Olmsted Illinois
Listed in Historical landmark, Ohio River Scenic Byway, Railroad Depot, Visited by Old Folks Adventures
110 Depot St, Olmsted, IL 62970, Olmsted, Illinois 62970
Built in 1872, the New York Central Railroad Depot preserves Olmsted's railroad heritage. Now a museum and National Register landmark, it tells the story of the Cairo and Vincennes Railroad and the trains that helped shape southern Illinois.
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