Cairo Historic District
Listed in Civil War, Civil War Trails, Historical place, National Underground Railroad Network to Freedom, Ohio River Scenic Byway, Trail of Tears, Visited by Old Folks Adventures
364-398 20th St, Cairo, Illinois 62914
Explore the historic streetscape of Cairo, Illinois, a strategic river town shaped by commerce, transportation, Civil War history, and its setting near the Ohio and Mississippi Rivers.
US Marine Hospital
Listed in Historical place, Tourist attraction
Northwestern Pkwy, Louisville, KY 40212, Louisville, Kentucky 40212
A rare surviving federal marine hospital tied to Louisville’s Ohio River history and the city’s 19th-century river trade.
Judge Joseph Holt House
6205 KY-144, Hardinsburg, Kentucky 40143
The Judge Joseph Holt House in Hardinsburg preserves the Kentucky home associated with Joseph Holt, a prominent Unionist who served in Lincoln’s administration and later became the Union army’s Judge Advocate General. It offers a thoughtful window into Kentucky’s divided Civil War history.
George Rogers Clark Homesite
Listed in Buffalo Trace Route, George Rogers Clark Sites, Historical place, Ohio River Scenic Byway, Pioneer History, Revolutionary War
1021 Harrison Ave, Clarksville, Indiana 47129
A Clarksville landmark marking the later home of Revolutionary War leader George Rogers Clark, with a chance to reflect on the town’s early frontier history near the Falls of the Ohio.
Missouri Mines State Historic Site
0492, 4000 State Hwy 32, Park Hills, Missouri 63601
Explore Missouri’s lead-mining legacy at a museum housed in the former St. Joe Minerals milling complex. Exhibits, machinery, and mineral specimens reveal the geology, industry, and communities of the Old Lead Belt.
Battle of Richmond Battlefield Park
1546 Battlefield Memorial Hwy, Richmond, KY 40475, Richmond, Kentucky 40475
Walk a Civil War battlefield with trails, historic buildings, and a visitor center in Richmond, Kentucky.
Ste. Geneviève Missouri
99 S Main St, Ste. Genevieve, Missouri 63670
Ste. Geneviève brings Missouri’s French colonial past to life with historic homes, vertical-log architecture, and a preserved downtown. Its National Historical Park and historic sites make it a memorable stop for travelers who enjoy architecture and local history.
Modoc Rock Shelter National Historic Landmark
6921-6851 Co Rd 7, Prairie Du Rocher, Illinois 62277
Modoc Rock Shelter preserves thousands of years of Native American history in a sheltered bluff overlooking the Mississippi River valley. Its archaeological record offers a fascinating glimpse into the changing lifeways of southern Illinois.
Bollinger Mill State Historic Site
Listed in Historical place, Native American Heritage Sites, State park, Trail of Tears, Visited by Old Folks Adventures
113 Bollinger Mill Rd, Burfordville, Missouri 63739
Explore a four-story, water-powered gristmill built in 1867 and Missouri's oldest covered bridge at this memorable Whitewater River historic site in Burfordville.
Mound City Shipyards
Listed in Civil War, Civil War Trails, Historical place, Ohio River Scenic Byway, Visited by Old Folks Adventures
217 S 4th St, Mound City, Illinois 62963
A historic Mound City riverfront site connected with the Union naval base, shipbuilding, repairs, and supply operations that supported Civil War campaigns in the Western Theater.
Cairo Historic District
Listed in Civil War, Civil War Trails, Historical place, National Underground Railroad Network to Freedom, Ohio River Scenic Byway, Trail of Tears, Visited by Old Folks Adventures
364-398 20th St, Cairo, Illinois 62914
Explore the historic streetscape of Cairo, Illinois, a strategic river town shaped by commerce, transportation, Civil War history, and its setting near the Ohio and Mississippi Rivers.
US Marine Hospital
Listed in Historical place, Tourist attraction
Northwestern Pkwy, Louisville, KY 40212, Louisville, Kentucky 40212
A rare surviving federal marine hospital tied to Louisville’s Ohio River history and the city’s 19th-century river trade.
Judge Joseph Holt House
6205 KY-144, Hardinsburg, Kentucky 40143
The Judge Joseph Holt House in Hardinsburg preserves the Kentucky home associated with Joseph Holt, a prominent Unionist who served in Lincoln’s administration and later became the Union army’s Judge Advocate General. It offers a thoughtful window into Kentucky’s divided Civil War history.
George Rogers Clark Homesite
Listed in Buffalo Trace Route, George Rogers Clark Sites, Historical place, Ohio River Scenic Byway, Pioneer History, Revolutionary War
1021 Harrison Ave, Clarksville, Indiana 47129
A Clarksville landmark marking the later home of Revolutionary War leader George Rogers Clark, with a chance to reflect on the town’s early frontier history near the Falls of the Ohio.
Missouri Mines State Historic Site
0492, 4000 State Hwy 32, Park Hills, Missouri 63601
Explore Missouri’s lead-mining legacy at a museum housed in the former St. Joe Minerals milling complex. Exhibits, machinery, and mineral specimens reveal the geology, industry, and communities of the Old Lead Belt.
Battle of Richmond Battlefield Park
1546 Battlefield Memorial Hwy, Richmond, KY 40475, Richmond, Kentucky 40475
Walk a Civil War battlefield with trails, historic buildings, and a visitor center in Richmond, Kentucky.
Ste. Geneviève Missouri
99 S Main St, Ste. Genevieve, Missouri 63670
Ste. Geneviève brings Missouri’s French colonial past to life with historic homes, vertical-log architecture, and a preserved downtown. Its National Historical Park and historic sites make it a memorable stop for travelers who enjoy architecture and local history.
Modoc Rock Shelter National Historic Landmark
6921-6851 Co Rd 7, Prairie Du Rocher, Illinois 62277
Modoc Rock Shelter preserves thousands of years of Native American history in a sheltered bluff overlooking the Mississippi River valley. Its archaeological record offers a fascinating glimpse into the changing lifeways of southern Illinois.
Bollinger Mill State Historic Site
Listed in Historical place, Native American Heritage Sites, State park, Trail of Tears, Visited by Old Folks Adventures
113 Bollinger Mill Rd, Burfordville, Missouri 63739
Explore a four-story, water-powered gristmill built in 1867 and Missouri's oldest covered bridge at this memorable Whitewater River historic site in Burfordville.
Mound City Shipyards
Listed in Civil War, Civil War Trails, Historical place, Ohio River Scenic Byway, Visited by Old Folks Adventures
217 S 4th St, Mound City, Illinois 62963
A historic Mound City riverfront site connected with the Union naval base, shipbuilding, repairs, and supply operations that supported Civil War campaigns in the Western Theater.
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